In a recent piece on Soul Contracts/Agreements, the Keepers mentioned something they referred to as "Soul Fatigue," here is more detailed information on that.
Soul Fatigue can be experienced when someone has experienced a high level of trauma, physical illness or both. This may be carried over from previous lives which explains why even young children may experience depression or a general malaise about life. This can be an explanation as to why some do choose to walk away from current soul contracts, as they lack the spiritual strength to keep these commitments.
The remedy for this condition is joy and lightness, which is the true state of the soul. Spiritual work with a qualified shamanic or other practitioner that is well-versed in soul retrieval is useful, as it is not uncommon for aspects of the person's life force energies and soul power to be scattered and disassociated. Akashic record work is also useful as it is possible to work within the timeline to clear trauma or maladaptive energies that may have been carried forward. It is possible for one to undertake this healing process themselves, if they are connected to their own spiritual Guidance Team adequately. Light Tools such as herbal and flower essence remedies are also helpful, especially for those that are vibrationally sensitive to them. Depending on the severity of this condition, a restoration process may take a short time or several months or longer once the restorative remedies have been undertaken. ~ The Keepers, 9.26.11
NOTE: Solar flare, geo-magnetic activity and general ascension symptoms can produce some of the same symptoms of physical, emotional and spiritual fatigue; but this would not be considered the same phenomenon that the Keepers are referring to here.