Tiller is a teacher, researcher, author and consultant, and is currently Professor Emeritus of the Department of Materials Science and Engineering at Stanford University. He previously worked as an advisory physicist at Westinghouse Research Laboratories, and has published 275 scientific papers and three technical books in the field of materials science.

He has carried out experiments with highly trained Tibettan monks, and found that their intentions can condition space in a machine on the atomic and subatomic levels.